Global Burden of Disease
Diabetes is the most common human endocrine disease and the term covers a group of metabolic disorders whose central feature is elevated blood glucose, or hyperglycemia. While treatments have advanced in recent years, severe complications still sadly exist. The current difficulties in managing and treating diabetes can result in a deterioration of mulitple tissue types, and severe complications can include: diabetic retinopathy and blindness, leg/foot ulcers and amputations, neuropathies, kidney failure, cardiovascular disease and heart attacks, and strokes.
Diabetes can be divided into two main patient types:
The recent increase in prevalence of Type 2 diabetes among younger people, often accompanied by obesity, is a major source of concern for public health authorities as it implies significant increases in long-term healthcare costs. There is no cure for either IDDM or NIDDM and the effective treatment for both types hinges upon the tight regulation of blood glucose levels.
Sources: International Diabetes Federation, WHO & American Diabetes Association